This article is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before starting any new supplement or making changes to your medication regimen.
KEY TAKEAWAY
Both DGL gummies and DGL tablets deliver deglycyrrhizinated licorice to support stomach lining protection. Research suggests the chewable form may offer an advantage for acid reflux because it allows DGL to mix with saliva and coat the esophagus on the way down [1]. Gummies tend to have better taste compliance, while tablets are typically less expensive per serving. The best choice depends on whether you prioritize convenience and consistency or cost.
What Is DGL?
Deglycyrrhizinated licorice (DGL) is a form of licorice root extract with the compound glycyrrhizin removed. This matters because glycyrrhizin, while therapeutic, can raise blood pressure and cause potassium depletion with long-term use [2]. By removing it, DGL retains the gut-protective properties of licorice without the cardiovascular concerns.
DGL has been studied for decades as a natural approach to supporting digestive health. A landmark clinical trial found that DGL performed comparably to cimetidine (Tagamet) in supporting ulcer healing, with 91% of DGL patients showing improvement compared to 72% on the pharmaceutical [3]. The primary mechanism appears to be stimulating the stomach's natural mucus production — essentially strengthening the protective barrier between your stomach lining and digestive acid [4].
DGL is available in several forms: chewable tablets, capsules, powders, and gummies. The form you choose can affect how well it works, how consistently you take it, and how much you spend.
DGL Gummies: How They Work
DGL gummies are relatively new to the market. They deliver DGL extract in a soft, flavored chewable format — typically berry or fruit flavors. Because they taste good, people tend to actually take them consistently, which matters more than most people realize for a supplement that works best with daily use.
Key characteristics:
- Chewed and mixed with saliva before swallowing (important for DGL's mechanism)
- Pleasant taste encourages daily compliance
- Typically contain 350–400mg DGL per serving
- May include complementary ingredients like zinc or marshmallow root
- Generally more expensive per serving than tablets
DGL Tablets: How They Work
DGL chewable tablets have been the standard form for decades. They deliver DGL extract in a compressed tablet that you chew before swallowing. Traditional DGL tablets have a distinctly chalky, licorice-like taste that some people find unpleasant — this is the most commonly cited reason people stop taking DGL despite experiencing benefits [5].
Key characteristics:
- Chewed before swallowing (same saliva-mixing benefit as gummies)
- Chalky texture and strong licorice taste
- Typically contain 380–760mg DGL per serving
- Established track record — most clinical studies used this form
- More affordable per serving
Head-to-Head Comparison
| Criteria | DGL Gummies | DGL Tablets |
|---|---|---|
| Taste | Berry/fruit flavored, enjoyable | Chalky, strong licorice flavor |
| DGL per serving | 350–400mg typical | 380–760mg typical |
| Chewing required | Yes (built into the format) | Yes (must chew, not swallow whole) |
| Compliance rate | Higher — people look forward to taking them | Lower — taste leads to dropoff |
| Clinical evidence | Limited (newer format) | Extensive (decades of studies) |
| Cost per month | $25–40/month | $10–20/month |
| Portability | Good (doesn't melt easily) | Good (shelf stable) |
| Additional ingredients | May include zinc, pectin | Usually pure DGL extract |
Why Chewing Matters for DGL
Here's something most people miss: DGL appears to work best when it's chewed, not swallowed whole. Research suggests that mixing DGL with saliva activates certain compounds and allows the extract to begin coating the esophagus and stomach on the way down [1]. This is why DGL capsules (which you swallow whole) may be less effective than either gummies or chewable tablets for acid reflux specifically.
Both gummies and tablets satisfy this requirement. The difference is that gummies make chewing natural and enjoyable, while tablets require a conscious decision to chew something that doesn't taste great.
Who Should Choose DGL Gummies
DGL gummies may be the better choice if you:
- Have tried DGL tablets before and quit because of the taste. This is more common than you'd think. A supplement that works but sits in your cabinet doesn't help.
- Want to build a daily habit easily. Something that tastes good is easier to remember and stick with.
- Prefer a more modern supplement format. If chalky tablets feel outdated to you, gummies may feel more natural to incorporate.
- Don't mind paying more for convenience. The taste and compliance benefits come at a premium.
Who Should Choose DGL Tablets
DGL tablets may be the better choice if you:
- Want the most-studied form. The clinical research on DGL was conducted primarily using chewable tablets [3][4].
- Are watching your budget. Tablets typically cost 40–60% less per month.
- Don't mind the taste. Some people genuinely don't find the licorice flavor objectionable.
- Want higher DGL per serving. Tablets often contain more DGL extract per serving than gummies.
Can You Switch Between Forms?
Yes. DGL is DGL regardless of the delivery format. If you start with tablets and find the taste difficult, switching to gummies shouldn't affect the benefits — you're still getting the same active compound. The reverse is also true. Some people start with gummies to build the habit, then switch to tablets once it's established to save money.
If you're currently taking DGL in any form and considering switching, there's no need to taper or transition gradually. Just switch at your next dose. As always, consult your healthcare provider if you have questions about your specific situation.
The Bottom Line
Both DGL gummies and DGL tablets may help support stomach lining protection and provide relief from acid reflux symptoms. The science behind DGL is the same regardless of format — the difference comes down to taste, compliance, cost, and personal preference.
If the chalky taste of traditional DGL tablets has kept you from trying DGL, or caused you to quit, gummies like Belly Beans solve that problem. Research consistently shows that the best supplement is the one you actually take consistently [6]. If taste isn't an issue for you and budget matters more, tablets deliver proven DGL at a lower cost.
Disclosure: Morea Labs manufactures Belly Beans, a DGL gummy supplement. We believe in transparency about our perspective while providing balanced, evidence-based information.
Frequently Asked Questions
How much DGL should I take daily for acid reflux?
Clinical studies have typically used 380–760mg of DGL extract taken before meals [3]. Most DGL supplements recommend 1–2 servings before your first meal. Follow the dosage instructions on your specific product and consult your healthcare provider for personalized guidance.
Are DGL gummies as effective as DGL tablets?
Both forms deliver DGL extract and both require chewing, which research suggests may be important for effectiveness [1]. While most clinical studies used tablet forms, the active compound is the same. The primary advantage of gummies is better taste compliance — you're more likely to take them consistently.
Can I take DGL while on a PPI like omeprazole?
DGL is generally considered safe to take alongside PPIs, as they work through different mechanisms — PPIs reduce acid production while DGL supports the stomach's protective lining [4]. However, you should always discuss supplement use with your healthcare provider, especially if you're on prescription medications. Never stop taking prescribed medications without medical guidance.
How long does DGL take to provide relief?
Some people report initial symptom relief within 30 minutes of taking DGL, though research suggests that the full protective benefits build over days to weeks of consistent use [3]. Most clinical trials evaluated outcomes at 4–8 week intervals. Individual results vary significantly.
Is DGL safe for long-term use?
DGL (with glycyrrhizin removed) appears to be well-tolerated for long-term use based on available research [2]. The removal of glycyrrhizin addresses the blood pressure and potassium concerns associated with regular licorice. That said, discuss any long-term supplement use with your healthcare provider.
References
- Raveendra KR, et al. "An Extract of Glycyrrhiza glabra (GutGard) Alleviates Symptoms of Functional Dyspepsia." Evidence-Based Complementary and Alternative Medicine. 2012. PMID: 22235230
- Isbrucker RA, Burdock GA. "Risk and safety assessment on the consumption of Licorice root, its extract and powder as a food ingredient." Regulatory Toxicology and Pharmacology. 2006;46(3):167-192. PMID: 16884839
- Morgan AG, et al. "Comparison between cimetidine and Caved-S in the treatment of gastric ulceration." Gut. 1982;23(6):545-551. PMID: 7076028
- Larkworthy W, Holgate PF. "Deglycyrrhizinized liquorice in the treatment of chronic duodenal ulcer." Practitioner. 1975;215(1290):787-792. PMID: 775174
- Hawrelak JA, Myers SP. "Effects of two natural medicine formulations on irritable bowel syndrome symptoms." Journal of Alternative and Complementary Medicine. 2010;16(10):1065-1071. PMID: 20954962
- Vrijens B, et al. "A new taxonomy for describing and defining adherence to medications." British Journal of Clinical Pharmacology. 2012;73(5):691-705. PMID: 22486599
This content is provided for educational purposes and is not intended to replace professional medical advice, diagnosis, or treatment. Individual results may vary. If you are experiencing persistent symptoms, please consult a qualified healthcare provider.